Is SLN Biopsy using PINPOINT the New Gold Standard?

Recent papers demonstrate the accuracy of sentinel node biopsy vs. full lymphadenectomy, reducing cost and morbidity.



These papers show the benefit of using PINPOINT (SPY Technology) ICG identification of SLN vs. Tech 99 +Blue

A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study. Rossi et al, Jan 2017
Conclusion: Sentinel lymph nodes identified with indocyanine green have a high degree of diagnostic accuracy in detecting endometrial cancer metastases and can safely replace lymphadenectomy in the staging of endometrial cancer.

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Comparison of a sentinel lymph node and a selective lymphadenectomy algorithm in patients with endometrioid endometrial carcinoma and limited myometrial invasion. Eriksson et al.
Conclusion: Our findings support the use of either strategy for endometrial cancer staging, with no apparent detriment in adhering to the SLN algorithm. The clinical significance of disease detected on ultra staging and the role of adjuvant therapy is yet to be determined.

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Cost-Effectiveness of Sentinel Node Biopsy and Pathological Ultrastaging in Patients With Early-Stage Cervical Cancer. Brar, Hogen & Covens. Jan 2017
Conclusion: Although it was included only as an exploratory strategy in this study, SLNB with ICG has the potential to be the most cost-effective strategy.

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: Lymphatic Mapping—Gastric Cancerm Danny Sherwinter MD
: PINPOINT Lymphatic Mapping Nadeem Abu Rustum, Feb 2014
: Overlay Mode in GYN Surgery—PINPOINT S1 Camera

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